Structure of PDB 2qsc Chain H Binding Site BS01

Receptor Information

>2qsc Chain H (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QVQLVQSGGGLVQPGGSLRLSCAAFGFNFSSYVMHWVRQAPGQGLEYLSA
ISSDGETTYHANSVKGRFTSSRDNSKNTLFLQMGSLRTEDVAVYYCARDR
YYETSGSNAFDVWGQGTMVVVSSASTKGPSVFPLAPCTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSTQTYTCNVDHK
PSNTKVDKTVE

Ligand information

>2qsc Chain P (length=15) Species: 11696 (HIV-1 M:B_MN) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

RKRIHIGPGRAFYTT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2qsc Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	S52 Y58 Y97 N100D
Binding residue (residue number reindexed from 1)	S52 Y59 Y101 N108

External links

PDB	RCSB:2qsc, PDBe:2qsc, PDBj:2qsc
PDBsum	2qsc
PubMed	18068724

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