Structure of PDB 2puq Chain H Binding Site BS01

Receptor Information
>2puq Chain H (length=254) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHY
RGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLR
APFP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2puq Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa
Resolution2.05 Å
Binding residue
(original residue number in PDB)		H193 P321 D338 S339 C340 S344 S363 W364 G365 G367
Binding residue
(residue number reindexed from 1)		H41 P169 D186 S187 C188 S192 S211 W212 G213 G215
Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2puq, PDBe:2puq, PDBj:2puq
PDBsum2puq
PubMed17456045
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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