Structure of PDB 2mcp Chain H Binding Site BS01

Receptor Information
>2mcp Chain H (length=222) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVKLVESGGGLVQPGGSLRLSCATSGFTFSDFYMEWVRQPPGKRLEWIAA
SRNKGNKYTTEYSASVKGRFIVSRDTSQSILYLQMNALRAEDTAIYYCAR
NYYGSTWYFDVWGAGTTVTVSSESARNPTIYPLTLPPALSSDPVIIGCLI
HDYFPSGTMNVTWGKSGKDITTVNFPPALASGGRYTMSNQLTLPAVECPE
GESVKCSVQHDSNPVQELDVNC
Ligand information
Ligand IDPC
InChIInChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)/p+1
InChIKeyYHHSONZFOIEMCP-UHFFFAOYSA-O
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCC[N+](C)(C)C
CACTVS 3.341C[N+](C)(C)CCO[P](O)(O)=O
OpenEye OEToolkits 1.5.0C[N+](C)(C)CCOP(=O)(O)O
FormulaC5 H15 N O4 P
NamePHOSPHOCHOLINE
ChEMBLCHEMBL1235161
DrugBankDB03945
ZINCZINC000001532692
PDB chain2mcp Chain H Residue 223 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2mcp Structure at 4.5 Angstroms Resolution of a Phosphorylcholine-Binding Fab Structure at 4.5 Angstroms Resolution of a Phosphorylcholine-Binding Fab
Resolution3.1 Å
Binding residue
(original residue number in PDB)		Y33 R52 W107
Binding residue
(residue number reindexed from 1)		Y33 R52 W107
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0016064 immunoglobulin mediated immune response
Cellular Component
GO:0019814 immunoglobulin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2mcp, PDBe:2mcp, PDBj:2mcp
PDBsum2mcp
PubMed
UniProtP01789|HVM20_MOUSE Ig heavy chain V region M603

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