Structure of PDB 2j8u Chain H Binding Site BS01
Receptor Information
>2j8u Chain H (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRAVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>2j8u Chain J (length=9) Species:
9606
(Homo sapiens) [
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ALWGFFPVL
Receptor-Ligand Complex Structure
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PDB
2j8u
Single MHC mutation eliminates enthalpy associated with T cell receptor binding.
Resolution
2.88 Å
Binding residue
(original residue number in PDB)
Y7 E63 A66 V67 A69 H70 T73 D77 R97 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 A66 V67 A69 H70 T73 D77 R97 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2j8u
,
PDBe:2j8u
,
PDBj:2j8u
PDBsum
2j8u
PubMed
17825839
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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