Structure of PDB 2hoi Chain H Binding Site BS01

Receptor Information
>2hoi Chain H (length=322) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRTATLVSTAGVEKALSLGVTK
LVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATH
RLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVN
IVMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hoi Synapsis of loxP sites by Cre recombinase.
Resolution2.601 Å
Binding residue
(original residue number in PDB)		M44 S47 R81 L83 A84 K86 T87 Q90 K122 K132 R159 R173 R241 V242 K244 L256 S257 R259 A260 R282 Y283 H289 R292 W315 T316 N317 I320 Y324 R326
Binding residue
(residue number reindexed from 1)		M25 S28 R62 L64 A65 K67 T68 Q71 K103 K113 R140 R154 R222 V223 K225 L237 S238 R240 A241 R263 Y264 H270 R273 W296 T297 N298 I301 Y305 R307
Binding affinityPDBbind-CN: Kd=8.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:2hoi, PDBe:2hoi, PDBj:2hoi
PDBsum2hoi
PubMed17573343
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

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