Structure of PDB 2hfg Chain H Binding Site BS01
Receptor Information
>2hfg Chain H (length=220) Species:
9606
(Homo sapiens) [
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EVQLVESGGGLVQPGGSLRLSCAASGFTISSSSIHWVRQAPGKGLEWVAW
VLPSVGFTDYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARRV
CYNRLGVCAGGMDYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKD
YFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTY
ICNVNHKPSNTKVDKKVEPK
Ligand information
>2hfg Chain R (length=27) Species:
9606
(Homo sapiens) [
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APAPTPCNPAECFDPLVRHCVACGLLR
Receptor-Ligand Complex Structure
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PDB
2hfg
Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Resolution
2.61 Å
Binding residue
(original residue number in PDB)
S31 W50 L52 R95 C97 Y98 N99 G100B V100C C100D
Binding residue
(residue number reindexed from 1)
S31 W50 L52 R99 C101 Y102 N103 G106 V107 C108
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2hfg
,
PDBe:2hfg
,
PDBj:2hfg
PDBsum
2hfg
PubMed
16840730
UniProt
Q6N093
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