Structure of PDB 2f1d Chain H Binding Site BS01

Receptor Information
>2f1d Chain H (length=183) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRIGEVKRVTKETNVSVKINLDGTGVADSSSGIPFLDHMLDQLASHGLFD
VHVRATGDVHIDDHHTNEDIALAIGTALLKALGERKGINRFGDFTAPLDE
ALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLH
IRQLAGENSHHIIEATFKAFARALRQATETDPR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain2f1d Chain H Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2f1d Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		H47 H169 E173
Binding residue
(residue number reindexed from 1)		H38 H160 E164
Annotation score1
Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
Biological Process
GO:0000105 L-histidine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2f1d, PDBe:2f1d, PDBj:2f1d
PDBsum2f1d
PubMed16338409
UniProtP34047|HIS5A_ARATH Imidazoleglycerol-phosphate dehydratase 1, chloroplastic (Gene Name=HISN5A)

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