Structure of PDB 2b1a Chain H Binding Site BS01

Receptor Information
>2b1a Chain H (length=226) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIQLEQSGAEVKKSGESLKISCQTSGYSFSDYWIGWVRQMPGKGLEWMGI
FYPGDSDSRYSPSFEGQVTMSADRSTNTAHLQWSSLKPSDTALYYCARLG
GDYEDSGADAFDFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALG
CLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSL
GTQTYICNVNHKPSNTKVDKKVEPKS
Ligand information
>2b1a Chain P (length=16) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TRKSIHLGPGRAFYAT
Receptor-Ligand Complex Structure
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PDB2b1a Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
Resolution2.348 Å
Binding residue
(original residue number in PDB)
D31 Y32 W33 Y52 D54 D56 L95 D98 E100 D100A S100B G100C A100D
Binding residue
(residue number reindexed from 1)
D31 Y32 W33 Y52 D55 D57 L99 D102 E104 D105 S106 G107 A108
External links