Structure of PDB 1qdu Chain H Binding Site BS01

Receptor Information
>1qdu Chain H (length=88) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDI
LTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFP
Ligand information
Receptor-Ligand Complex Structure
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PDB1qdu The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S339 Y340 R341 N342 P343 W348
Binding residue
(residue number reindexed from 1)		S22 Y23 R24 N25 P26 W31
Enzymatic activity
Enzyme Commision number 3.4.22.61: caspase-8.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1qdu, PDBe:1qdu, PDBj:1qdu
PDBsum1qdu
PubMed10508784
UniProtQ14790|CASP8_HUMAN Caspase-8 (Gene Name=CASP8)

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