Structure of PDB 1mcp Chain H Binding Site BS01

Receptor Information
>1mcp Chain H (length=222) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVKLVESGGGLVQPGGSLRLSCATSGFTFSDFYMEWVRQPPGKRLEWIAA
SRNKGNKYTTEYSASVKGRFIVSRDTSQSILYLQMNALRAEDTAIYYCAR
NYYGSTWYFDVWGAGTTVTVSSESARNPTIYPLTLPPALSSDPVIIGCLI
HDYFPSGTMNVTWGKSGKDITTVNFPPALASGGRYTMSNQLTLPAVECPE
GESVKCSVQHDSNPVQELDVNC
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1mcp Chain H Residue 223 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1mcp Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y33 R52
Binding residue
(residue number reindexed from 1)		Y33 R52
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0016064 immunoglobulin mediated immune response
Cellular Component
GO:0019814 immunoglobulin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mcp, PDBe:1mcp, PDBj:1mcp
PDBsum1mcp
PubMed3097327
UniProtP01789|HVM20_MOUSE Ig heavy chain V region M603

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