Structure of PDB 1fos Chain H Binding Site BS01

Receptor Information
>1fos Chain H (length=58) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANMLREQV
AQLKQKVM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1fos Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.
Resolution3.05 Å
Binding residue
(original residue number in PDB)		R268 N271 R272 R279
Binding residue
(residue number reindexed from 1)		R4 N7 R8 R15
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1fos, PDBe:1fos, PDBj:1fos
PDBsum1fos
PubMed7816143
UniProtP05412|JUN_HUMAN Transcription factor Jun (Gene Name=JUN)

[Back to BioLiP]