Structure of PDB 1fnt Chain H Binding Site BS01
Receptor Information
>1fnt Chain H (length=196) Species:
4932
(Saccharomyces cerevisiae) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAA
DTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVA
GYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEE
TVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
Ligand information
Ligand ID
MG
InChI
InChI=1S/Mg/q+2
InChIKey
JLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341
[Mg++]
Formula
Mg
Name
MAGNESIUM ION
ChEMBL
DrugBank
DB01378
ZINC
PDB chain
1fnt Chain H Residue 1002 [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1fnt
Structural basis for the activation of 20S proteasomes by 11S regulators.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
I163 D166 S169
Binding residue
(residue number reindexed from 1)
I163 D166 S169
Annotation score
4
Enzymatic activity
Catalytic site (original residue number in PDB)
T1 D17 R19 K33 G47 S129 D166 S169
Catalytic site (residue number reindexed from 1)
T1 D17 R19 K33 G47 S129 D166 S169
Enzyme Commision number
3.4.25.1
: proteasome endopeptidase complex.
Gene Ontology
Molecular Function
GO:0004175
endopeptidase activity
GO:0004298
threonine-type endopeptidase activity
GO:0005515
protein binding
Biological Process
GO:0006508
proteolysis
GO:0010499
proteasomal ubiquitin-independent protein catabolic process
GO:0043161
proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603
proteolysis involved in protein catabolic process
Cellular Component
GO:0000502
proteasome complex
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005839
proteasome core complex
GO:0019774
proteasome core complex, beta-subunit complex
GO:0034515
proteasome storage granule
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:1fnt
,
PDBe:1fnt
,
PDBj:1fnt
PDBsum
1fnt
PubMed
11081519
UniProt
P38624
|PSB1_YEAST Proteasome subunit beta type-1 (Gene Name=PRE3)
[
Back to BioLiP
]