Structure of PDB 1dl7 Chain H Binding Site BS01

Receptor Information
>1dl7 Chain H (length=112) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVQLKESGPGLVAPSQSLSITCTVSGFSLTGYGVNWVRQPPGKGLEWLGM
IWGDGSTDYNSALKSRLNISKDKSKSQVFLRMYSLQTDDTARYYCARDYG
PYWGQGTLVTVS
Ligand information
Ligand IDNCH
InChIInChI=1S/C11H17N2O6P/c1-13(2,3)8-9-18-20(16,17)19-11-6-4-10(5-7-11)12(14)15/h4-7H,8-9H2,1-3H3/p+1
InChIKeyNAIXASFEPQPICN-UHFFFAOYSA-O
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C[N+](C)(C)CCOP(=O)(O)Oc1ccc(cc1)[N+](=O)[O-]
CACTVS 3.341C[N+](C)(C)CCO[P@@](O)(=O)Oc1ccc(cc1)[N+]([O-])=O
ACDLabs 10.04[O-][N+](=O)c1ccc(OP(=O)(OCC[N+](C)(C)C)O)cc1
OpenEye OEToolkits 1.5.0C[N+](C)(C)CCO[P@](=O)(O)Oc1ccc(cc1)[N+](=O)[O-]
CACTVS 3.341C[N+](C)(C)CCO[P](O)(=O)Oc1ccc(cc1)[N+]([O-])=O
FormulaC11 H18 N2 O6 P
NameP-NITROPHENYL-PHOSPHOCHOLINE
ChEMBL
DrugBank
ZINCZINC000004521729
PDB chain1dl7 Chain L Residue 999 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dl7 The structural basis of repertoire shift in an immune response to phosphocholine.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		W52 Y99
Binding residue
(residue number reindexed from 1)		W52 Y99
Annotation score1
Binding affinityPDBbind-CN: -logKd/Ki=6.49,Kd=0.32uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0016064 immunoglobulin mediated immune response
Cellular Component
GO:0019814 immunoglobulin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1dl7, PDBe:1dl7, PDBj:1dl7
PDBsum1dl7
PubMed10859335
UniProtP01820|HVM44_MOUSE Ig heavy chain V region PJ14

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