Structure of PDB 7a01 Chain G5 Binding Site BS01

Receptor Information
>7a01 Chain G5 (length=137) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKR
AGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDN
KLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR
Ligand information
>7a01 Chain K3 (length=1801) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucucccacuuggauaa
cugugguaauucuagagcuaauacaugccgacgggcgcugacccccuucg
cgggggggaugcgugcauuuaucagaucaaaaccaacccggucagccccu
ggcgggcgccggcggcuuuggugacucuagauaaccucgggccgaucgca
cgccccccguggcggcgacgacccauucgaacgucugcccuaucaacuuu
cgaugguagucgccgugccuaccauggugaccacgggugacggggaauca
ggguucgauuccggagagggagccugagaaacggcuaccacauccaagga
aggcagcaggcgcgcaaauuacccacucccgacccggggagguagugacg
aaaaauaacaauacaggacucuuucgaggcccuguaauuggaaugagucc
acuuuaaauccuuuaacgaggauccauuggagggcaagucuggugccagc
agccgcgguaauuccagcuccaauagcguauauuaaaguugcugcaguua
aaaagcucguaguuggaucuugggagcgggcgggcgcgcccguccccgcc
ccuugccucucggcgcccgggcccgaagcguuuacuuugaaaaaauuaga
guguucaaagcaggcccgagccgccuggauaccgcagcuaggaauaaugg
aauaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauu
aagagggacggccgggggcauucguauugcgccgcuagaggugaaauucu
uggaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuu
cauuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucg
uaguuccgaccauaaacgaugccgaccggcgaugcggcggcguuauuccc
augacccgccgggcagcuuccgggaaaccaaagucuuuggguuccggggg
gaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcaccac
caggaguggagccugcggcuuaauuugacucaacacgggaaaccucaccc
ggcccggacacggacaggauugacagauugauagcucuuucucgauuccg
ugggugguggugcauggccguucuuaguugguggagcgauuugucugguu
aauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgacccc
cgagcggucggcgucccccaacuucuuagagggacaaguggcguucagcc
acccgagauugagcaauaacaggucugugaugcccuuagauguccggggc
ugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgccggc
aggcgcggguaacccguugaaccccauucgugauggggaucggggauugc
aauuauuccccaugaacgaggaauucccaguaagugcgggucauaagcuu
gcguugauuaagucccugcccuuuguacacaccgcccgucgcuacuaccg
auuggaugguuuagugaggcccucggaucggccccgccggggucggccca
cggcccuggcggagcgcugagaagacggucgaacuugacuaucuagagga
aguaaaagucguaacaagguuuccguaggugaaccugcggaaggaucauu
a
...<<<<<.{.[[[[>>>>><<<.<<<<<<...<.<<.........<<<.
<<<...<....<......<..........>.....>.>.......<<...
.....<<<......<<......<....................<<.....
<<.............>>......>>.........<<<<...<<<<<....
..>>>>>...>>>>....<<<<<......(((((......<....<<...
....>>......>................>>>>>...........<<<<.
.<<<......>>>.>>>>...>......>>....>>>.<<<....<<<..
...<<<<<<.........>>>>>>.>>>......>>>...<<<.<<<<..
..>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>
.>...>>>>>>.........<<<....<<<.....>>>..>>>......>
>.>.....<<.<<<<<<.<........>.>>.>>>>..>>....<.<<..
...............>>......>..<<<<<((......<<<<.....<<
..))>>.......>>>>.>>>>>..>>>>>>.>>>.........<.<[[.
....<.<<....<<.<<.....<<.<<<<<<<<<<..>>>>>..>>>>>>
>........<<<<.<<<<>>>>>>>>.....<<<<<<.<.......<<..
.<.......>..<<<.......>>>....>>......>.>>>..>>>...
.....<.....<<<.<.........)))))...>.>>>.....>....>>
....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>.
.....>>>>>>>>..>>.......<<....>>...>>>>..>..>>>.>>
>...>>....>>.>....<<<<<<<...<...<<<<.........>>>>.
..>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<.....
.>>>>>>>>>>.>..>>>...<<..]]>>...>>.....>>>.>.>.<<<
......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<
..<<<<...<<<.<<<<<<.......<........>...........<<<
<<.<....<<<<<........<<..<<........>>.>>.......>>>
>>...<<.<<<..<<.<<<<<<....<<<.<<<<......>>...<<<..
....>>>...>>.>>>....<<<.......<<.....<<.....<<.<<.
.<......>>>..>>.....>>.....>>........<<<<<.....>>>
>>........>>>....>>>.>>>.....>>>>>>>.....>.>>>>>..
.>>.>>>>.>>>.....<<.<<<................<<<.<<<<...
.>>>>.>>>..............>>>.>>......<.....<<<<<....
......>>>>>.....>......>>>>......<<<<<<<.......>>>
>>>>.......>>...>>>>>>>>>>.>>.......<<.<..<<<<.<<.
...<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<..<.......
..>..>>>>>>>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.
>>>>...>.>>.........<<<<<<<<<....>>>>>>>>>........
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7a01 The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
R23 R24 K25 F28 G35 V36 G37 R38 R39 Y40 W82 F83 N85 R86 Q87 K88 H120 R121 R130 V131 R132 G133 Q134 H135 T136 K137 T138 G140 R142
Binding residue
(residue number reindexed from 1)
R18 R19 K20 F23 G30 V31 G32 R33 R34 Y35 W77 F78 N80 R81 Q82 K83 H115 R116 R125 V126 R127 G128 Q129 H130 T131 K132 T133 G135 R137
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7a01, PDBe:7a01, PDBj:7a01
PDBsum7a01
PubMed33296660
UniProtG1TPG3|RS18_RABIT Small ribosomal subunit protein uS13 (Gene Name=RPS18)

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