Structure of PDB 8upo Chain G Binding Site BS01

Receptor Information
>8upo Chain G (length=225) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNE
ALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIK
DMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPG
NDDAIRAVTLYLGAVAATVREGRSQ
Ligand information
>8upo Chain D (length=1524) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaauugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacg
aguggcggacgggugaguaaugucugggaaacugccugauggagggggau
aacuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagag
ggggaccuucgggccucuugccaucggaugugcccagaugggauuagcua
guaggugggguaacggcucaccuaggcgacgaucccuagcuggucugaga
ggaugaccagccacacuggaacugagacacgguccagacuccuacgggag
gcagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugc
cgcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagg
aagggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaag
caccggcuaacuccggccagcagcccgguaauacggagggugcaagcguu
aaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaagucaga
ugugaaauccccgggcucaaccugggaacugcaucugauacuggcaagcu
ugagucucguagagggggguagaauuccagguguagcggugaaaugcgua
gagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagacug
acgcucaggugcgaaagcguggggagcaaacaggauuagauacccuggua
guccacgccguaaacgaugucgacuuggagguugugcccuugaggcgugg
cuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgcaag
guuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcaugu
gguuuaauucgauaacgcgaagaaccuuaccuggucuugacauccacgga
aguuuucagagaugagaaugugccuucgggaaccgugagacaggugcugc
auggcugucgucagcucguguugugaaauguuggguuaagucccgcaacg
agcgcaacccuuauccuuuguugccagcgguccggccgggaacucaaagg
agacugccagugauaaacuggaggaagguggggaugacgucaagucauca
ugcccuuacgaccagggcuacacacgugcuacaauggcgcauacaaagag
aagcgaccucgcgagagcaagcggaccucauaaagugcgucguaguccgg
auuggagucugcaacucgacuccaugaagucggaaucgcuaguaaucgug
gaucagaaugccacggugaauacguucccgggccuuguacacaccgccgu
acaccaugggaguggguugcaaaagaaguagguagcuuaaccuucgggag
ggcgcuuaccacuuugugauucaugacuggggugaagucgaacaagguaa
ccguaggggccugcgguuggauca
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<..<<<<<<<<<......>>>>>>.>>>>>.
.>>>>>......<<.......<<<<<<<..<<...<<<<<<<.<.<<...
..<<<<<......>>>>>......>>.>.....<<<....>>>....<<<
<<<..<<....>>>>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<.
.<<<<<<<.........>>>>>>>>>>......>>>..<<<<<<<<....
>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>
...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>
>>>..<<<<......<<<<....>>>>.....>>>>..<<.<<<<<....
..<.<<<<<<<<.......>>>>>>>>.>........>>>>>....>>.<
<<<<(((...<<<<<.......)))........>>>>>>>>>>..>>>>>
>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<
<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>.
..<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>>...
...>>>>>>>>...........<<....>>.>>>>>>>..>>>>.>>>>.
..>>>...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...
>>>>>>>>..........<<<<<<.<<<<<<<<<<<<<.....>>>>>>>
>>>>>>..<<..))>>.....>>>>>>.>>>.<<<......<<<<....>
>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<
<<<......<<......>>..........<<<<<<<......<<<<<<<.
.<<<<<<<....>>>>>>>...<......>..>>>>>.>>.<<<.<....
<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>
>>>.....<<<<.<<<<<<<...<<..<<<.....>>>>>....>>>>>>
>.....<<<<<.....>>>>>........>>>>.........>>>...>>
>.>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<
..<<...<<<....>>>...>>....>>>.....>>>>>>>......<..
..<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<
<.........>>>>>>>......>>...>>>>>>>>>>.>>......<<.
.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<<<<..<<<..>>>.>
>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>....>>........<<
<<<<<<<..>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB8upo Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Resolution5.5 Å
Binding residue
(original residue number in PDB)		R21 W23 P25 R95 G98 G99 T102 N103 K105 T106 S110 R113 K132 I171 K174
Binding residue
(residue number reindexed from 1)		R19 W21 P23 R93 G96 G97 T100 N101 K103 T104 S108 R111 K130 I169 K172
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8upo, PDBe:8upo, PDBj:8upo
PDBsum8upo
PubMed39117885
UniProtC3TPN2

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