Structure of PDB 8tof Chain G Binding Site BS01

Receptor Information
>8tof Chain G (length=369) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEEPKELLEKDSKGNIIKLNEPSTISEDSKVSVTGLPLNKGPSEKIKRES
LWNNRNDLKTFLTENMTEESNIRSTIGWNGDENEDFCSACNQSGSFLCCD
TCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFINNSMATLKKIESNF
IKQNNNVKIFAKLLFNIDSHNPKQFQLPNYIKETFPAVKTGSRGQYSDEN
DKIPLTDRQLFNTSYGQSITKLDSYNPDTHIDSNSGKFLICYKCNQTRLG
SWSHPENSRLIMTCDYCQTPWHLDCVPRASFKNLGSKWKCPLHSPTKVYK
KIVNYKVWKKQRLINKNQLYYEPLQKIGYQNNGNIQIIPDFKITQIDENS
IKYDFFDKIYKSKMVQKRK
Ligand information
>8tof Chain N (length=176) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tctgggtggtggccgttttcgttgtttttttctgtctcgtgccaggagac
tagggagtaatccccttggcggttaaaacgcgggggacagcgcgtacgtg
cgtttaagcggtgctagagctgtctacgaccaattgagcggcctcggcac
cgggattctgatatcgcgcgtgatct
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8tof Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
A317 K320 K321
Binding residue
(residue number reindexed from 1)
A141 K144 K145
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060195 negative regulation of antisense RNA transcription
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0032221 Rpd3S complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8tof, PDBe:8tof, PDBj:8tof
PDBsum8tof
PubMed38065958
UniProtQ04779|RCO1_YEAST Transcriptional regulatory protein RCO1 (Gene Name=RCO1)

[Back to BioLiP]