Structure of PDB 8qdv Chain G Binding Site BS01

Receptor Information
>8qdv Chain G (length=226) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKN
VVGARRSSWRVVSSIEQKTEKKQQMAREYREKIETELRDICNDVLSLLEK
FLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAF
EISKKEMQPTHPIRLGLALNFSVFYYEILNSPKACSLAKTAFDEAIAELD
TLSEESYKDSTLIMQLLRDNLTLWTS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qdv 14-3-3zeta binding increases cytosolic phospho-Tau solubility by decreasing its condensation, aggregation, and microtubule association
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R56 R60 R127 Y128 L172 N173 N224
Binding residue
(residue number reindexed from 1)		R56 R60 R124 Y125 L169 N170 N220
External links
PDB RCSB:8qdv, PDBe:8qdv, PDBj:8qdv
PDBsum8qdv
PubMed
UniProtP63104|1433Z_HUMAN 14-3-3 protein zeta/delta (Gene Name=YWHAZ)

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