Structure of PDB 8p1f Chain G Binding Site BS01

Receptor Information
>8p1f Chain G (length=204) Species: 6523 (Lymnaea stagnalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDV
VFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTP
QLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREI
SVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLN
FRKK
Ligand information
Ligand IDWCW
InChIInChI=1S/C12H16N2O2/c13-12(11(15)16)6-8-14(9-7-12)10-4-2-1-3-5-10/h1-5H,6-9,13H2,(H,15,16)
InChIKeyFPGAOFXYANTSRQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7c1ccc(cc1)N2CCC(CC2)(C(=O)O)N
CACTVS 3.385NC1(CCN(CC1)c2ccccc2)C(O)=O
FormulaC12 H16 N2 O2
Name4-azanyl-1-phenyl-piperidine-4-carboxylic acid
ChEMBL
DrugBank
ZINC
PDB chain8p1f Chain G Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8p1f Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Y108 W162 Y204 Y211
Binding residue
(residue number reindexed from 1)		Y89 W143 Y185 Y192
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8p1f, PDBe:8p1f, PDBj:8p1f
PDBsum8p1f
PubMed
UniProtP58154|ACHP_LYMST Acetylcholine-binding protein

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