Structure of PDB 8h40 Chain G Binding Site BS01

Receptor Information
>8h40 Chain G (length=314) Species: 1163 (Anabaena) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YTEDSIRLYLQEIGRIRLLRADEEIELARKIADLLELERVRERLSEKLER
DPRDSEWAEAVQLPLPAFRYRLHIGRRAKDKMVQSNLRLVVSIAKKYMNR
GLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQS
RTIRLPVHLYETISRIKKTTKLLSQEMGRKPTEEEIATRMEMTIEKLRFI
AKSAQLPISLETPIGKEEDSRLGDFIESDGETPEDQVSKNLLREDLEKVL
DSLSPRERDVLRLRYGLDDGRMKTLEEIGQIFNVTRERIRQIEAKALRKL
RHPNRNSVLKEYIR
Ligand information
>8h40 Chain 1 (length=66) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
attttgtagctacttatacaaaattcaggaaaatttttctgtataatggg
agctgtcacggatgca
Receptor-Ligand Complex Structure
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PDB8h40 Cryo-EM structure of the transcription activation complex NtcA-TAC
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D80 R83 L86 L94 R164 L165 K171 F180 Y204 K205 S207 T208 Y209 W212 R220 R230 H234 R362 E363
Binding residue
(residue number reindexed from 1)		D4 R7 L10 L18 R88 L89 K95 F104 Y128 K129 S131 T132 Y133 W136 R144 R154 H158 R286 E287
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8h40, PDBe:8h40, PDBj:8h40
PDBsum8h40
PubMed38177666
UniProtP26683|SIGA_NOSS1 RNA polymerase sigma factor SigA (Gene Name=sigA)

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