Structure of PDB 8fn9 Chain G Binding Site BS01

Receptor Information
>8fn9 Chain G (length=215) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRVFPHPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWI
VFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRV
DMRDGQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFST
EDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKG
HEFSIPFVEMKMRPY
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8fn9 Chain G Residue 1401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fn9 Protein-protein interactions between tenascin-R and RPTP zeta /phosphacan are critical to maintain the architecture of perineuronal nets.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D1282 D1284 A1286 T1288
Binding residue
(residue number reindexed from 1)		D154 D156 A158 T160
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8fn9, PDBe:8fn9, PDBj:8fn9
PDBsum8fn9
PubMed37356715
UniProtQ92752|TENR_HUMAN Tenascin-R (Gene Name=TNR)

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