Structure of PDB 8cst Chain G Binding Site BS01

Receptor Information
>8cst Chain G (length=292) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYTEDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDIDRAIAYLFPSGLF
EKRARPVMKHPEQIFPRQRAIQWGEDGRPFHYLFYTGKQSYYSLMHDVYG
MLLNLEKHGSRWLIKEELEEMLVEKLSDLDYMQFIRLLEKLLTSQCGAAE
EEFVQRFRRSVTLESKKQLIEPVQYDEQGMAFSKSEGKRKTAKAEAIVYK
HGSGRIKVNGIDYQLYFPITQDREQLMFPFHFVDRLGKHDVTCTVSGGGR
SAQAGAIRLAMAKALCSFVTEDEVEWMRQAGLLTTDPRVRER
Ligand information
>8cst Chain A (length=888) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucaaauaaagcuaaaacucaccugaguuguaaaaaacuccaguuga
cacaaaauagacuacgaaaguggcuuuaacauaucugaacacacaauagc
uaagacccaaacugggauuagauaccccacuaugcuuagcccuaaaccuc
aacaguuaaaucaacaaaacugcucgccagaacacuacgagccacagcuu
aaaacucaaaggaccuggcggugcuucauaucccucuagaggagccuguu
cuguaaucgauaaaccccgaucaaccucaccaccucuugcucagccuaua
uaccgccaucuaacccugaugaaggcuacaaaguacguuaggucaaggug
uagcccaugagguggcaagaaaugggcuacauuuucuaccccagaaaacu
acgauagcccuuaugaaacuuaagggucgaagguggauuuagcaguaaac
ugagaguagagugcuuaguugaacagggcccugaagcgcgucacccuccu
caaguauacuucaaaggacauuuaacuaaaaccccuacgcauuuauauag
aggagacaaguaaguguacuggaaagugcacuuggacg
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<....<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>.........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<.....<<<<<<......<<<.<<<.<<<......>>>..>>>.>>>
.............<<....>>.>>>>>>.....>>>>...>>>>....<<
<<<<...<<...<<<<.........>>>>...>>>>>>>>..........
<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<....>>>>
.....>>..>>>>>>......<<<<<<<...<<<.<<<<<..<<<<<<<<
.......<<........>>..........<<<<<<<.......<<.<<<.
.<<.<<<<.<..<<<<<.....>>>.......>>..>.>.>>>....>>>
>>>>....>>>>>>>.....>>>>>>>>.....<<<<.....>>>>....
.<....<<<<<<<.......>>>>>>>....>.....>>>>>.....<<<
<<<<.........>>>>>>>.....>>>...>>>>>>>.......<<<<<
<..<<<<<......<<<....<<.....>>...>>>.......>>>>>.>
>>>>>......<<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB8cst Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution2.85 Å
Binding residue
(original residue number in PDB)
L216 R276 K277 T278 I306 G336 S338 R375 V376 R377 E378
Binding residue
(residue number reindexed from 1)
L129 R189 K190 T191 I219 G249 S251 R288 V289 R290 E291
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8cst, PDBe:8cst, PDBj:8cst
PDBsum8cst
PubMed36482135
UniProtP82933|RT09_HUMAN Small ribosomal subunit protein uS9m (Gene Name=MRPS9)

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