Structure of PDB 8caz Chain G Binding Site BS01

Receptor Information
>8caz Chain G (length=144) Species: 679895 (Escherichia coli BW25113) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRRRRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLASELE
AFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARK
RGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHY
Ligand information
>8caz Chain A (length=460) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaac
cuuaccuggucuugacauccacggaaguuuucagagaugagaaugugccu
ucgggaaccgugagacaggugcugcauggcugucgucagcucguguugug
aaauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcc
agcgguccggccgggaacucaaaggagacugccagugauaaacuggagga
agguggggaugacgucaagucaucauggcccuuacgaccagggcuacaca
cgugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgg
accucauaaagugcgucguaguccggauuggagucugcaacucgacucca
ugaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacg
uucccgggcc
<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>......
....<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<..
...>...>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<...
.>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<<
..<<<.....>>>>>....>>>>>>>.....<<<<<.....>>>>>....
....>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>
>>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>..
..>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>
....>.....>>>>>>....<<<<<<<.........>>>>>>>......>
>...>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8caz Structural conservation of antibiotic interaction with ribosomes.
Resolution2.11 Å
Binding residue
(original residue number in PDB)		P2 R3 R4 R5 R10 K25 N28 L30 M31 V32 D33 G34 K35 K36 S37 T38 I42 R78 R79 R92 R95 R102 R109 K114 M116 R119
Binding residue
(residue number reindexed from 1)		P1 R2 R3 R4 R5 K20 N23 L25 M26 V27 D28 G29 K30 K31 S32 T33 I37 R68 R69 R82 R85 R92 R99 K104 M106 R109
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8caz, PDBe:8caz, PDBj:8caz
PDBsum8caz
PubMed37550453
UniProtP02359|RS7_ECOLI Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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