Structure of PDB 7z6h Chain G Binding Site BS01

Receptor Information
>7z6h Chain G (length=317) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTST
ILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGF
KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRC
TRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNI
LQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITEL
KTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEK
IQLSSLIAAFQVTRDLI
Ligand information
Receptor-Ligand Complex Structure
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PDB7z6h Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction.
Resolution3.59 Å
Binding residue
(original residue number in PDB)
G97 I98
Binding residue
(residue number reindexed from 1)
G78 I79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
GO:0019899 enzyme binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding
GO:1900264 positive regulation of DNA-directed DNA polymerase activity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005663 DNA replication factor C complex
GO:0031390 Ctf18 RFC-like complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7z6h, PDBe:7z6h, PDBj:7z6h
PDBsum7z6h
PubMed35819203
UniProtP40937|RFC5_HUMAN Replication factor C subunit 5 (Gene Name=RFC5)

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