Structure of PDB 7z6h Chain G Binding Site BS01
Receptor Information
>7z6h Chain G (length=317) Species:
9606
(Homo sapiens) [
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LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTST
ILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGF
KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRC
TRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNI
LQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITEL
KTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEK
IQLSSLIAAFQVTRDLI
Ligand information
>7z6h Chain X (length=22) [
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atatacgggctgctgttgacaa
Receptor-Ligand Complex Structure
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PDB
7z6h
Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction.
Resolution
3.59 Å
Binding residue
(original residue number in PDB)
G97 I98
Binding residue
(residue number reindexed from 1)
G78 I79
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003689
DNA clamp loader activity
GO:0005515
protein binding
GO:0005524
ATP binding
GO:0016887
ATP hydrolysis activity
GO:0017116
single-stranded DNA helicase activity
GO:0019899
enzyme binding
Biological Process
GO:0006260
DNA replication
GO:0006261
DNA-templated DNA replication
GO:0006281
DNA repair
GO:0032508
DNA duplex unwinding
GO:1900264
positive regulation of DNA-directed DNA polymerase activity
Cellular Component
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005663
DNA replication factor C complex
GO:0031390
Ctf18 RFC-like complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:7z6h
,
PDBe:7z6h
,
PDBj:7z6h
PDBsum
7z6h
PubMed
35819203
UniProt
P40937
|RFC5_HUMAN Replication factor C subunit 5 (Gene Name=RFC5)
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