Structure of PDB 7z0s Chain G Binding Site BS01

Receptor Information
>7z0s Chain G (length=250) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVDCGGCNGCEI
EIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQSA
PDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATL
YGFAMALGLLEQKIHARGPGELDEQPAEILHGDMVQPLRVKVDREARRLA
GYRYGRQIADDYLTQLGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEAR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7z0s Chain G Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7z0s Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		G47 C48 G50 C51 C115 C145 P146
Binding residue
(residue number reindexed from 1)		G44 C45 G47 C48 C112 C142 P143
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006007 glucose catabolic process
GO:0009061 anaerobic respiration
GO:0015944 formate oxidation
GO:0019645 anaerobic electron transport chain
GO:1902600 proton transmembrane transport
Cellular Component
GO:0009326 formate dehydrogenase complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7z0s, PDBe:7z0s, PDBj:7z0s
PDBsum7z0s
PubMed36104349
UniProtP16433|HYCG_ECOLI Formate hydrogenlyase subunit 7 (Gene Name=hycG)

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