Structure of PDB 7vly Chain G Binding Site BS01

Receptor Information
>7vly Chain G (length=297) Species: 1639 (Listeria monocytogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSKRDRLRVAWRSTFIQGSWNYERMQNGGWAFSMIPAIKKLYKTKEDRSS
ALKRHLEFFNTHPYIASPILGVTLALEEERANGAEVDDVAIQGVKVGMMG
PLAGVGDPVFWFTIRPMLGALGASLALSGNILGPILFFVAWNVIRWGFMW
YTQEFGYKAGSKITDDLSGGLLQDITKGASILGMFVLAALVQRWVNIQFA
PIISKVKLDEGAYIDWSHLPQGAQGIKTALQQQQAGLALSEIKVTTLQNN
LDNLIPGLAAVALTFLCMWLLKKKISPIIIILGLFVVGIVGHLIGLL
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain7vly Chain G Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7vly Structural Basis of Pore Formation in the Mannose Phosphotransferase System by Pediocin PA-1.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		Q23 W26 N66 T67 D113 W117
Binding residue
(residue number reindexed from 1)		Q17 W20 N60 T61 D107 W111
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7vly, PDBe:7vly, PDBj:7vly
PDBsum7vly
PubMed34851716
UniProtQ8YAM0

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