Structure of PDB 7unw Chain G Binding Site BS01

Receptor Information
>7unw Chain G (length=175) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRVAKNPVKLPAGVEIKLAGQQLSIKGAKGALELKVHPSVEVIQDSGELR
FAARNGDQQTRAMAGTTRALVNNMVVGVSQGFERKLQLVGVGYKAQAKGQ
VLSLSLGFSHPVDYELPAGIVAETPSQTDILIKGIDKQLVGQVAAEIRDF
RPPEPYKGKGVRYADEVVRRKEAKK
Ligand information
>7unw Chain A (length=2884) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggucaagugaagaagcgcauacgguggaugccuuggcagucagaggcgau
gaaagacgugguagccugcgaaaagcuucggggagucggcaaacagacuu
ugauccggagaucucugaaugggggaacccaccuaggauaaccuagguau
cuuguacugaauccauaggugcaagaggcgaaccaggggaacugaaacau
cuaaguacccugaggaaaagaaaucaaccgagauucccuuaguaguggcg
agcgaacggggauuagcccuuaagcuucauugauuuuagcggaacgcucu
ggaaagugcggccauagugggugauagccccguacgcgaaaggaucuuug
aagugaaaucgaguaggacggagcacgagaaacuuugucugaacaugggg
ggaccauccuccaaggcuaaauacuacugacugaccgauagugaaccagu
accgugagggaaaggcgaaaagaaccccggagaggggagugaaauagaac
cugaaaccguaugcguacaagcagugggagccuacuuguuaggugacugc
guaccuuuuguauaaugggucagcgacuuauauucaguggcaagcuuaac
cguauaggguaggcguagcgaaagcgagucuuaauagggcguuuagucgc
uggguauagacccgaaaccgggcgaucuauccaugagcagguugaagguu
agguaacacugacuggaggaccgaacccacucccguugaaaagguagggg
augacuuguggaucggagugaaaggcuaaucaagcucggagauagcuggu
ucuccucgaaagcuauuuagguagcgccucauguaucacucuggggggua
gagcacuguuucggcuagggggucaucccgacuuaccaaaccgaugcaaa
cuccgaauacccagaagugccgagcaugggagacacacggcgggugcuaa
cguccgucgugaaaagggaaacaacccagaccgccagcuaaggucccaaa
guugugguuaagugguaaacgaugugggaaggcuuagacagcuaggaggu
uggcuuagaagcagccacccuuuaaagaaagcguaauagcucacuagucg
agucggccugcgcggaagauguaacggggcucaaaccacacaccgaagcu
gcgggugucacggugacgcgguagaggagcguucuguaagccugugaagg
ugaguugagaagcuugcuggagguaucagaagugcgaaugcugacaugag
uaacgacaaugggugugaaaaacacccacgccgaaagaccaaggguuccu
gcgcaacguuaaucgacgcaggguuagucgguuccuaaggcgaggcugaa
aagcguagucgaugggaaacagguuaauauuccuguacuucugguuacug
cgauggagggacggagaaggcuaggccagcuuggcguugguuguccaagu
uuaaggugguaggcugaaaucuuagguaaauccgggguuucaaggccgag
agcugaugacgagucgucuagaugacgaagugguugaugccaugcuucca
agaaaagcuucuaagcuucagguaaccaggaaccguaccccaaaccgaca
cagguggucggguagagaauaccaaggcgcuugagagaacucgggugaag
gaacuaggcaaaauggcaccguaacuucgggagaaggugcgccggcuagg
gugaaggauuuacuccguaagcucuggcuggucgaagauaccaggccgcu
gcgacuguuuauuaaaaacacagcacucugcaaacacgaaaguggacgua
uagggugugacgccugcccggugccggaagguuaauugaugggguuagcg
caagcgaagcucuugaucgaagccccgguaaacggcggccguaacuauaa
cgguccuaagguagcgaaauuccuugucggguaaguuccgaccugcacga
auggcguaacgauggcggcgcugucuccacccgagacucagugaaauuga
aaucgcugugaagaugcaguguauccgcggcuagacggaaagaccccgug
aaccuuuacuguagcuuugcacuggacuuugagccugcuuguguaggaua
ggugggaggcuuugaagcguggacgccaguucgcguggagccauccuuga
aauaccacccuggcaugcuugagguucuaacucugguccguaauccggau
cgaggacaguguauggugggcaguuugacuggggcggucuccuccuaaag
aguaacggaggaguacgaaggugcgcucagaccggucggaaaucggucgc
agaguauaaaggcaaaagcgcgcuugacugcgagacagacacgucgagca
gguacgaaaguaggucuuagugauccggugguucuguauggaagggccau
cgcucaacggauaaaagguacuccggggauaacaggcugauaccgcccaa
gaguucauaucgacggcgguguuuggcaccucgaugucggcucaucacau
ccuggggcugaagccggucccaaggguauggcuguucgccauuuaaagug
guacgcgagcuggguuuagaacgucgugagacaguucggucccuaucugc
cguggacguuugagauuugagaggggcugcuccuaguacgagaggaccgg
aguggacgaaccucugguguuccgguugucacgccaguggcauugccggg
uagcuauguucggaaaagauaaccgcugaaagcaucuaagcgggaaacuu
gccucaagaugagaucucacugggaacuugauuccccugaagggccgucg
aagacuacgacguugauaggcuggguguguaagcguugugaggcguugag
cuaaccaguacuaauugcccgugaggcuugacca
<<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<...
...<<<<<<.[[.(((.>>>.....<<<<<<<..<<<)))..]].>>>..
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>...<<<<<.....<<....
.>>....>>>>>...(((.....<<<<<<..<<<<<..<<<...<<<.<.
.....>.>>>((......<<<.....))>>>...>>>....>>>>>..>>
>>>>...........<<<<<<<<.........>>>>>>>>......<<<<
<..<<<<>>>>>..)))......]].>>>>>>>.]]..............
.<<....>>....]].........<<<<.....>>>>.............
.....>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>
...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<
<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>
>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<
<<......>>>>>>.....>>>...<<<.<<.<<........>>.>>>>>
....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>.
.<<<<<<....<<<<<....>>>>>.<<<<<<<<..<<<<<<<<<.....
<<<...<<<.<<<<...<<................>>...>>>>.>>>..
>>.>.....>>>>>>.>>>....>>>>>>>.>...<<<<<<<<<<.....
.>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((...
..<<<<<<...........<<..<<<<<..<<........<<<<<.<<..
.<<<<.......>>>>...>>........<<........>>..>>>>>..
..>>..>>>>>.>>...........)))......>>>>>>.>>>...>>>
>>>><<<<<<<.>>>>>>>....>>>>>><.<<<<<...<<<......<<
<<<<<<....>>>>>>>>...>>>..>>>>>..>.....>>>>>><....
..<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<
<<<...<<.....>>.>>>>>>....((<<<<<<<...<<<...<<<...
.>>>...>>>...>>>..<<<<<........>>>>>))<<<<<<<<<<<<
<...<<<<....<<<<..<<<..<<<<<<<<<<<...((((...>>>>>>
<<..<<<....<<<<<<<<<<<..<<.....>>.>>>>>>>..>>>>...
.>>>...>><..<<<<<<..>>>>>>...>>>>>>...>>>...>>>.>.
.......>>>>...>>....>>>>>>>>>>>>>>>..>>.....<<....
..>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<
...............<<<<<.....<..>......>>>>><<<<<<<<<<
<<...<<<.....>>>....>>>>>>>>>>>>............<<<<<<
<<<..<<<.........>>>..<<<<<<<.....<<<....>>>......
.>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<.......<<<<<<.<<.
...>>..>>>>>>.......>>>>>>>>>..>>>>><<<<<<.......>
>>>>>........<...........<<<<<<.....>>>>>>.....>..
..>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>..
...<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[
[<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<<.<.<............
<<<<...<<............<<<....>>>.........>>........
.....>>>>...>.>.>>>>>>>>>>>...<<<.<<<<<<.....>>>>>
>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<.....
......>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>..
...<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>
>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>
>>.............>>>>..]]>>>>.......<<<<.<.<<<<<<...
<<.......>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..
<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>
>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>
>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>
>>>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>.
..>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>
.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<<<<<<<<
.......>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>
>...>>>>>.>>>...>>>>..>..>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7unw Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation
Resolution2.6 Å
Binding residue
(original residue number in PDB)		R3 Q60 R62 A63 M64 G66 T67 A70 S110 H111 Q139 G142 Q143 Y157 K158 K160 K172 K175
Binding residue
(residue number reindexed from 1)		R2 Q59 R61 A62 M63 G65 T66 A69 S109 H110 Q138 G141 Q142 Y156 K157 K159 K171 K174
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7unw, PDBe:7unw, PDBj:7unw
PDBsum7unw
PubMed
UniProtQ9HWF0|RL6_PSEAE Large ribosomal subunit protein uL6 (Gene Name=rplF)

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