Structure of PDB 7oue Chain G Binding Site BS01

Receptor Information
>7oue Chain G (length=241) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMIARIIGEIGIEGARFIEENIDEQFKALRYLSKGIDSETFVKLVIAN
SLVSYQLTGKGEQWWWEFAKYFYGRDVKSIYLAYKEFLPNSRFNRRLIPQ
KLSRIRRVETFLSTLTEERIEEYYGDMSSLWGSIARALGVDKESKTVVFS
VKMFGYAARIVLSTFNPYPMEIPIPEDSRIVKLTKKLTNEKPRKFWMKIA
RESGVPPLHIDSILWPLLGGASIDSAPPELRDKLAELIKII
Ligand information
Receptor-Ligand Complex Structure
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PDB7oue Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Resolution2.04 Å
Binding residue
(original residue number in PDB)
Q53 T55 R92 R93 L94
Binding residue
(residue number reindexed from 1)
Q56 T58 R95 R96 L97
Enzymatic activity
Enzyme Commision number 3.2.2.-
4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
Gene Ontology
Molecular Function
GO:0000702 oxidized base lesion DNA N-glycosylase activity
GO:0003824 catalytic activity
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0016829 lyase activity
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function

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Biological Process
External links
PDB RCSB:7oue, PDBe:7oue, PDBj:7oue
PDBsum7oue
PubMed36300625
UniProtQ9UZY0|AGOG_PYRAB N-glycosylase/DNA lyase (Gene Name=PYRAB10170)

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