Structure of PDB 7oue Chain G Binding Site BS01
Receptor Information
>7oue Chain G (length=241) Species:
272844
(Pyrococcus abyssi GE5) [
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GSHMIARIIGEIGIEGARFIEENIDEQFKALRYLSKGIDSETFVKLVIAN
SLVSYQLTGKGEQWWWEFAKYFYGRDVKSIYLAYKEFLPNSRFNRRLIPQ
KLSRIRRVETFLSTLTEERIEEYYGDMSSLWGSIARALGVDKESKTVVFS
VKMFGYAARIVLSTFNPYPMEIPIPEDSRIVKLTKKLTNEKPRKFWMKIA
RESGVPPLHIDSILWPLLGGASIDSAPPELRDKLAELIKII
Ligand information
>7oue Chain F (length=9) [
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tttctttct
Receptor-Ligand Complex Structure
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PDB
7oue
Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Resolution
2.04 Å
Binding residue
(original residue number in PDB)
Q53 T55 R92 R93 L94
Binding residue
(residue number reindexed from 1)
Q56 T58 R95 R96 L97
Enzymatic activity
Enzyme Commision number
3.2.2.-
4.2.99.18
: DNA-(apurinic or apyrimidinic site) lyase.
Gene Ontology
Molecular Function
GO:0000702
oxidized base lesion DNA N-glycosylase activity
GO:0003824
catalytic activity
GO:0003906
DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0016787
hydrolase activity
GO:0016799
hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0016829
lyase activity
GO:0140078
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Biological Process
GO:0006281
DNA repair
GO:0006284
base-excision repair
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Molecular Function
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Biological Process
External links
PDB
RCSB:7oue
,
PDBe:7oue
,
PDBj:7oue
PDBsum
7oue
PubMed
36300625
UniProt
Q9UZY0
|AGOG_PYRAB N-glycosylase/DNA lyase (Gene Name=PYRAB10170)
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