Structure of PDB 7n19 Chain G Binding Site BS01
Receptor Information
>7n19 Chain G (length=179) Species:
9606
(Homo sapiens) [
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KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEF
Ligand information
>7n19 Chain I (length=13) Species:
32630
(synthetic construct) [
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GGIGSDNKVTRRG
Receptor-Ligand Complex Structure
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PDB
7n19
CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope.
Resolution
2.38 Å
Binding residue
(original residue number in PDB)
Q9 E11 S53 F54 N62 V65 N69 I72 M73
Binding residue
(residue number reindexed from 1)
Q8 E10 S52 F53 N61 V64 N68 I71 M72
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:7n19
,
PDBe:7n19
,
PDBj:7n19
PDBsum
7n19
PubMed
34410304
UniProt
P01903
|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)
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