Structure of PDB 7kui Chain G Binding Site BS01

Receptor Information

>7kui Chain G (length=49) Species: 269446 (Rous sarcoma virus (strain Schmidt-Ruppin A))

GPPVKIRIETGEWEKGWNVLVWGRGYAAVKNRDTDKVIWVPSRKVKPDI

Ligand information

>7kui Chain I (length=18)

aatgttgtcttatgcaat

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7kui Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
• Resolution: 3.4 Å
• Binding residue (original residue number in PDB): Y246 W259 R263
• Binding residue (residue number reindexed from 1): Y26 W39 R43

Enzymatic activity

• Enzyme Commision number: 2.7.7.-
  2.7.7.49: RNA-directed DNA polymerase.
  2.7.7.7: DNA-directed DNA polymerase.
  3.1.-.-
  3.1.26.4: ribonuclease H.
  3.4.23.-

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0008270 zinc ion binding

Biological Process

• GO:0015074 DNA integration

External links

• PDB: RCSB:7kui, PDBe:7kui, PDBj:7kui
• PDBsum: 7kui
• PubMed: 33712691
• UniProt: P03354|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)