Structure of PDB 7cwv Chain G Binding Site BS01

Receptor Information
>7cwv Chain G (length=495) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIDLKQYEFWFLVGSQYLYGLETLKKVEQQASKIVDSLNDDPIFPSKIVL
KPVLKSSSEITEIFEKANADPKCAGVIVWMHTFSPSKMWIRGLSINKKPL
LHLHTQYNREIPWDTIDMDYMNLNQSAHGDREHGFIHARMRLPRKVVVGH
WEEKEVREKIAKWMRVACAIQDGRMGQIVRFGDNMREVASTEGDKVEAQI
KLGWSINTWGVGELAERVKAVPEREVEELLKEYREKYIMPEDEYSLKAIR
EQAKIEIALREFLKEKNAVGFTTTFEDLHDLPQLPGLAVQRLMEEGYGFG
AEGDWKAAGLVRAIKVMGTSLPGGTSFMEDYTYHLTPGNELVLGAHMLEV
CPTIAKEKPRIEVHPLSIGGKADPARLVFDGQEGPAVNASIVDMGNRFRL
VVNKVLSVPIERKMPKLPTARVLWKPLPDFKRATTAWILAGGSHHTAFST
AIDVEYLIDWAEALEIEYVVIDENLDLEDFKKELRWNELYWGLLK
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7cwv Chain G Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cwv Crystal structure of Arabinose isomerase from hyper thermophilic bacterium Thermotoga maritima (TMAI) wt
Resolution3.53 Å
Binding residue
(original residue number in PDB)		E302 E329 H346 H444 H445
Binding residue
(residue number reindexed from 1)		E302 E329 H346 H444 H445
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.4: L-arabinose isomerase.
Gene Ontology
Molecular Function
GO:0008733 L-arabinose isomerase activity
GO:0016853 isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Biological Process
GO:0005996 monosaccharide metabolic process
GO:0019568 arabinose catabolic process
GO:0019569 L-arabinose catabolic process to xylulose 5-phosphate
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cwv, PDBe:7cwv, PDBj:7cwv
PDBsum7cwv
PubMed
UniProtQ9WYB3|ARAA_THEMA L-arabinose isomerase (Gene Name=araA)

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