Structure of PDB 7aso Chain G Binding Site BS01

Receptor Information
>7aso Chain G (length=155) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFDLVE
QRSGRDALEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGL
RWLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKAF
AHYRW
Ligand information
>7aso Chain X (length=1415) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacguuagcggcggacgggugaguaacacguggau
aaccuaccuauaagacugggauaacuucgggaaaccguagcuaauaccgg
auaauauagugaaagacacuuauagauggauccgcgcugcauuagcuagu
ugguaagguaacggcuuaccaaggcaacgaugcauagccgaccugagagg
gugaucggccacacuggaacugagacacgguccagacuccuacgggaggc
agcaguagggaaucuuccgcaaugggcgaaagccugacggagcaacgccg
cgugagugaugaaggucuaucguaaaacucuguuauuagggagaacauau
gucacaucuugacguaccuaaucagaaagccacggcuaacuacgugccag
cagccgcgguaauacguagguggcaagcguuauccggaauuauugggcgu
aaagcgcgcguaggcgguuuuuuaagucugaugugaaagcccacggcuca
accguggagggucauuggaaacuggaaaacuugagugcagaagaggaaag
uggaauuccauguguagcggugaaaugcgcgagauauggaggaacaccag
uggcgaaggcgacuuucuggucuguaacugacgcugaugugcgaaagcgu
ggggaucaaacaggauuagauacccugguaguccacgccguaaacgauga
gugcuaaguguuagggggugccccuuagugcugcagcuaacgcauuaagc
acuccgccuggggaguacgaccgcaagguugaaacucaaaggaauugacg
gggacccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaa
gaaccuuaccaaaucuugacaucacaaagugacagguggugcaugguugu
cgucagcucgugucgugagauguuggguuaagucccgcaacgagcgcaac
ccuuaagcuuaguugccaucauuaaguugggcacucuaaguugacugccg
gugacaaaccggaggaagguggggaugacgucaaaucaucaugccccuua
ugauuugggcuacacacgugcuacaauggacaauacaaagggcagcgaaa
ccgcgaggucaagcaaucccauaaaguuguucucaguucggauuguaguc
ugcaacucgacuacaugaagcuggaaucgcuaguaaucguagaucagcau
gcuacggugaauacguucccgggucuuguacacaccgcccgucacaccac
gagguuuguaacacccgaagccgguggaguaaccuuuuaggagcuagccg
ucgaaggugggacaaaugggggugaagucguaacaagguagccguaucgg
aaggugcggcuggau
......((...<..<<<..))...<....<<<<..<<<<<<.<.....<<
<.......<<..............>>.......<<..........<<<..
.......<<......<...........<<<....>>>............>
.......................>>......>>>...<<<..........
.<.................>...........>>>..<<..<<........
>>.....>>.>>.<<<<..<.........>.>>>>...<......>....
....>>>..........<......<<......>>....>...>..>>>>>
>.....<.......<....>......>.......................
........................................<<<.......
...............>>>........>>>>....>...........<.<<
.....<.<....<<..<<<<.....<<...............<<<<....
.>>>>...............>>....>>>>...<<<.<<<<...<.....
................<.<......>.>......................
..<......>.......>..>>>>..>>>....>>....>.>........
......<...<<<<.........>>>>...>.................[.
..((...<<.<<...<.<..>.>...>>.>>....((..>>)).....))
...]..>....<........<......>......>....>>>..>...<.
..<<.<<.......<<.......<<.........................
..........<<......................<<.<<...<<......
.....<<<<<<<<<....>>>....<<......>>....>>>>>>.....
<.<<..............................................
<<.....>>...........>>.>................>>.>>>>...
....>>...........>>....................<..........
<......>..........>.........................<<<...
...........>>>.............>>.......<...<.........
..>...>.............>>.>>..>........<.........<<..
....<.......<<.....<.<<<...<<<............>>>..>>>
.>....>>......>.....>>...........>........<<<.....
.....>>>.......
Receptor-Ligand Complex Structure
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PDB7aso Staphylococcus aureus 70S after 30 minutes incubation a 37C
Resolution3.11 Å
Binding residue
(original residue number in PDB)		P2 V7 D11 N28 K29 M31 D33 G34 K35 R36 G37 T38 R41 K76 A77 R78 V89 R95 T98 L99 K114 T115 M116 E117 R155 W156
Binding residue
(residue number reindexed from 1)		P1 V6 D10 N27 K28 M30 D32 G33 K34 R35 G36 T37 R40 K75 A76 R77 V88 R94 T97 L98 K113 T114 M115 E116 R154 W155
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aso, PDBe:7aso, PDBj:7aso
PDBsum7aso
PubMed
UniProtA0A077VHU6

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