Structure of PDB 7afa Chain G Binding Site BS01

Receptor Information
>7afa Chain G (length=144) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLA
QRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAM
RWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMA
Ligand information
>7afa Chain 1 (length=456) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaacc
uuaccuggucuugacauccacggaaguuuucagagaugagaaugugccuu
cgggaaccgugagacaggugcugcauggcugucgucagcucguguuguga
aauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcca
gcgguccggccgggaacucaaaggagacugccagugauaaacuggaggaa
gguggggaugacgucaagucaucauggcccuuacgaccagggcuacacac
gugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgga
ccucauaaagugcgucguaguccggauuggagucugcaacucgacuccau
gaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacgu
ucccgg
<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<<..
..>>..>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....
>>>..<<<<......>>>>..>>>>>>.....<<<..<<<<<<<...<<.
.<<<.....>>>>>....>>>>>>>.....<<<<<.....>>>>>.....
....>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>
>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>...
.>>>.....>>>>>>>...........<<<<<<<........>>>>>>>.
.........>>>>>>....<<<<<<<.........>>>>>>>......>>
...>>>
Receptor-Ligand Complex Structure
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PDB7afa A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Resolution2.95 Å
Binding residue
(original residue number in PDB)
P2 R3 R4 V6 Q9 R10 K25 N28 L30 M31 V32 D33 G34 K35 K36 T38 R78 R79 R102 R109 K114 M116 R119
Binding residue
(residue number reindexed from 1)
P1 R2 R3 V5 Q8 R9 K24 N27 L29 M30 V31 D32 G33 K34 K35 T37 R77 R78 R101 R108 K113 M115 R118
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7afa, PDBe:7afa, PDBj:7afa
PDBsum7afa
PubMed34088665
UniProtP02359|RS7_ECOLI Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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