Structure of PDB 7a23 Chain G Binding Site BS01

Receptor Information

>7a23 Chain G (length=382) Species: 3712 (Brassica oleracea)

FTLNFGPQHPAAHGVLRLVLEMNGEVVERAEPHIGLLHRGTEKLIEYKTY
LQALPYFDRSDYVSMMAQEHAYSLAVEKLLNCEVPLRAQYIRVLFCEITR
ILNHLLALTTHAMDVGALTPFLWAFEEREKLLEFYERVSGARMHASFIRP
GGVAQDLPLGLCRDIDSFTQQFASRIDELEEMLTGNRIWKQRLVDIGTVT
AQQAKDWGFSGVMLRGPGVCWDLRRAAPYDVYDQLDFDVPVGTRGDCYDR
YCIRIEEMRQSLRIIVQCLNQMPSGMIKADDRKLCPPSRCRMKLSMESSI
HHFELYTEGFSVPASSTYTAVEAPKGEFGVFLVSNGSNRPYRCKIRAPGF
AHLQGLDFMSKHHMLADVVTIIGTQDIVFGEV

Ligand information

>7a23 Chain r (length=24) Species: 3712 (Brassica oleracea)

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Receptor-Ligand Complex Structure

Structure summary

• PDB: 7a23 Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): V36 D248 V249 P250 V251 R254
• Binding residue (residue number reindexed from 1): V26 D238 V239 P240 V241 R244

Enzymatic activity

• Enzyme Commision number: 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).

Gene Ontology

Molecular Function

• GO:0008137 NADH dehydrogenase (ubiquinone) activity
• GO:0016491 oxidoreductase activity
• GO:0016651 oxidoreductase activity, acting on NAD(P)H
• GO:0048038 quinone binding
• GO:0051287 NAD binding

Biological Process

• GO:0006120 mitochondrial electron transport, NADH to ubiquinone
• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0005739 mitochondrion
• GO:0045271 respiratory chain complex I

External links

• PDB: RCSB:7a23, PDBe:7a23, PDBj:7a23
• PDBsum: 7a23
• PubMed: 33060577
• UniProt: P93306|NDUS2_ARATH NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 (Gene Name=NAD7)