Structure of PDB 6yal Chain G Binding Site BS01

Receptor Information
>6yal Chain G (length=263) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MARGPKKHLKRVAAPKHWMLDKLTSVFAPRPSTGPHKLRECLPLIIFLRN
KLKYALTGDEVKKICMQRFIKIDGKVRADITYPAGFMDVISIDKTGENFR
LIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYP
DPLIKMNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRER
HPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAE
ERDKRLAAKQSSG
Ligand information
>6yal Chain 2 (length=1744) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgccuacuuggauaacugugguaauu
cuagagcuaauacaugccgacggcgcugacucccuuugugugggaugcgu
gcauuuaucagaucaaaaccaacccggucggcggcuuuggugacucuaga
uaaccucgggccgaucgcagcccuccguggcggcgacgacccauucgaac
gucugcccuaucaacuuucgaugguagucgccgugccuaccauggugacc
acgggugacggggaaucaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacucccga
cccggggagguagugacgaaaaauaacaauacaggacucuuucgaggccc
uguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauuggag
ggcaagucuggucgcagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguugcugcaguuaaaaagcucguaguuggaucuuguggaggguuc
cccgccccuugccucucggcgccggcccgaagcguuuacuuugaaaaaau
uagaguguucaaagcaggcccgagccgccuggauaccgcagcuaggaaua
auggaauaggaccgcgguucuauuuuguugguuuucggaacugaggccau
gauuaagagggacggccgggggcauucguauugcgccgcuagaggugaaa
uucuuggaccggcgcaagacggaccagagcgaaagcauuugccaagaaug
uuuucauuaaucaagaacgaaagucggagguucgaagacgaucagauacc
gucguaguuccgaccauaaacgaugccgacuggcgaugcggcggcguuau
ucccaugacccgccgggcagcuuccgggaaaccaaagucuuuggguuccg
gggggaguaugguugcaaagcugaaacuuaaaggaauugacggaagggca
ccaccaggaguggagccugcggcuuaauuugacucaacacgggaaaccuc
acccggcccggacacggacaggauugacagauugauagcucuuucucgau
ucugugggugguggugcauggccguucuuaguugguggagcgauuugucu
gguuaauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcga
cccccgagcggucggcgucccccaacuucuuagagggacaaguggcguuc
agccacccgagauugagcaauaacaggucugugaugcccuuagaugucgg
ggcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgcc
ggcaggcgcggguaacccguugaaccccauucgugauggggaucggggau
ugcaauuauuccccaugaacgaggaauucccaguaagugcgggucauaag
cuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacua
ccgauuggaugguuuagugaggcccucggaucggcccgccggggugcccu
ggcggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaa
gucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[.........<<.....<<.<<<.....
>>>.>>......>>.........<<<...<<.<......>.>>...>>>.
[[..(((((.....<<<<<<<<<<<<.....>>>....<......>..))
)))......]]...<<<<.<<<......>>>.>>>>....]]]...}}..
..]]].<<<....<<<....<<<<<<<.........>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.........
.>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<<.
..>>>>..>>>......}}.......<<<<<<.<<.<<<....>>>.>>.
.>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..)))))).
]]]............{{.......{{...[[[.[[....<<<<.<<...>
>>>>>........<......<<..>>....>....<<<<<<.<.......
<<...<.......>.<<<<.......>>>>...>>......>.>>>..>>
>.......[[....(((((((.....>>>>>>>>>.)))))))...]]..
..]]....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......
>>>......>>>>>>>>..>>.......<<....>>...>>>>..>..>>
>.>>>...]]]...}}......<<<<<<<...<...<<<<.<.....>.>
>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<.
.....>>>>>>>>>>.>..>>>...<<..}}>>...>>.....>>>....
.<<<......<<<<....>>>>....>>>..]]]]..<<<<<.<<<<<<<
..<<..<<<<<..<<<.<<<<<<......<<........>>.........
.<<<<<......<<<<<<.......<<.<<<........>>>.>>.....
>>>>>>...<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<
<<......>>>...>>.>>>....<<<...<...<<<<..<<<<....<<
<..<<<<....>>>>.>>>....>>>>..>>>>..>.....<<<<<....
.>>>>>........>>>....>>>.>>>...>.>>>>>>>......>>>>
>...>>.>>>>.>>>.....<<.<<<........<.......<<<.<<<<
....>>>>.>>>....>.........>>>.>>......<.....<<<<<.
.........>>>>>.....>.....>>>>>.....<<<<<<<<.......
>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.
<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<<..>>>>
>>>.>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...
>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB6yal Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
M1 A2 R3 G4 K6 K7 H8 K10 V12 K16 M19 K22 L23 S25 F27 P29 R30 T33 G34 R49 T57 K62 K63 M66 Q67 K75 R77 R108 K128 V131 G132 K134 A144 T146 R148 K155 G186 A187 A219 R221 Q260 S261 S262 G263
Binding residue
(residue number reindexed from 1)
M1 A2 R3 G4 K6 K7 H8 K10 V12 K16 M19 K22 L23 S25 F27 P29 R30 T33 G34 R49 T57 K62 K63 M66 Q67 K75 R77 R108 K128 V131 G132 K134 A144 T146 R148 K155 G186 A187 A219 R221 Q260 S261 S262 G263
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6yal, PDBe:6yal, PDBj:6yal
PDBsum6yal
PubMed
UniProtG1TK17|RS4X_RABIT Small ribosomal subunit protein eS4 (Gene Name=RPS4X)

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