Structure of PDB 6w4m Chain G Binding Site BS01

Receptor Information
>6w4m Chain G (length=338) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMW
KNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCT
PAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEE
IIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGGDIRKAYCEINGTKWNK
VLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLF
NNTCITMKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNIT
GILLTRDGTSNETFRPGGGNIKDNWRSELYKYKVVQIE
Ligand information
>6w4m Chain N (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGRCAPTYCACV
Receptor-Ligand Complex Structure
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PDB6w4m Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
V255 A281 S365 G366 G367 D368 E370 I371 F382 N425 M426 W427 G429 T430 G473
Binding residue
(residue number reindexed from 1)
V136 A162 S224 G225 G226 D227 E229 I230 F241 N275 M276 W277 G279 T280 G319
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6w4m, PDBe:6w4m, PDBj:6w4m
PDBsum6w4m
PubMed32693837
UniProtA0A0M3KKW9

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