Structure of PDB 6vil Chain G Binding Site BS01

Receptor Information
>6vil Chain G (length=153) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQLWKWSGNPTQGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIG
RIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDV
QTISHKCQVVGREQYEQMMRGRKYQDQQDLYYLAGTYDPTTGRLVTADGV
PVL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vil BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis.
Resolution3.301 Å
Binding residue
(original residue number in PDB)
Y2537 W2558 Y2560 E2564 D2585 N2587 T2591
Binding residue
(residue number reindexed from 1)
Y48 W69 Y71 E75 D96 N98 T102
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding

View graph for
Molecular Function
External links
PDB RCSB:6vil, PDBe:6vil, PDBj:6vil
PDBsum6vil
PubMed33139953
UniProtQ3UHR0|BAHC1_MOUSE BAH and coiled-coil domain-containing protein 1 (Gene Name=Bahcc1)

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