Structure of PDB 6mfp Chain G Binding Site BS01

Receptor Information
>6mfp Chain G (length=341) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENF
NMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIH
YCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLA
EEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNDIRKAYCEINGTKWN
KVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQL
FNNTCIKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITG
ILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
Ligand information
>6mfp Chain N (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGRCAPTYCACV
Receptor-Ligand Complex Structure
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PDB6mfp Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
S365 G366 G367 D368 E370 I371 S375 N425 M426 W427 G429 T430 G473
Binding residue
(residue number reindexed from 1)
S225 G226 G227 D228 E230 I231 S235 N274 M275 W276 G278 T279 G322
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6mfp, PDBe:6mfp, PDBj:6mfp
PDBsum6mfp
PubMed31776278
UniProtA0A0M3KKW9

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