Structure of PDB 6hb4 Chain G Binding Site BS01

Receptor Information
>6hb4 Chain G (length=193) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hb4 DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region.
Resolution3.05 Å
Binding residue
(original residue number in PDB)
K52 V54 L58 T77 R157 Y162 Q179 L182 K183 W189 Y211 R232 R233 T234
Binding residue
(residue number reindexed from 1)
K9 V11 L15 T34 R114 Y119 Q136 L139 K140 W146 Y168 R189 R190 T191
Binding affinityPDBbind-CN: Kd=4.4nM
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6hb4, PDBe:6hb4, PDBj:6hb4
PDBsum6hb4
PubMed31114891
UniProtQ00059|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)

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