Structure of PDB 6g63 Chain G Binding Site BS01

Receptor Information
>6g63 Chain G (length=493) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIE
EAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDKEERG
NKGAALTTFISLAGSYLVLMPNNPRAGGISRGDDRTELKEALASLGMGLI
VRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRA
FRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFS
HYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEE
TAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAV
RQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNE
SLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQD
GVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM
Ligand information
>6g63 Chain B (length=23) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB6g63 Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
Resolution3.95 Å
Binding residue
(original residue number in PDB)		M1 R3 Q22 Y269 Q270
Binding residue
(residue number reindexed from 1)		M1 R3 Q22 Y252 Q253
Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:6g63, PDBe:6g63, PDBj:6g63
PDBsum6g63
PubMed30270108
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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