Structure of PDB 6c66 Chain G Binding Site BS01

Receptor Information
>6c66 Chain G (length=832) Species: 269800 (Thermobifida fusca YX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYLSPGLRDTIAS
SMETDEEHAGHCIAFWAGLHDIGKLTREFQQQIAIDLSAYPGEELSGEQR
SHAAATGKWLPFALPSLGYPNGGLVTGLVAQMLGGHHGTFHPHPSFQSRN
PLAEFGFSSPHWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL
ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPSLLDAAGLKPN
GLQASLAKHLPCLCTGPGLVLITAPMGEGKTEAAYHVADLLGKATGRPGR
FLALPTMATADQMHTRLKEYAMGRKRGLLAPWAVGTIDQALMAVLRAKHN
ALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGTLDVPVVLLSATLH
HSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDARIGKVTRSS
DVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLAKELTPLVKQAAIIC
TTVAEAQGVYDLLSQWFATLPDLYLLHSRFPNRQRTEITATIVDLFGKEG
AQSGRRPTVLVATQVVEQSLDLDVDLMISDLAPVSLLLQRAGRCWRHEHL
GIINRPQWAKQPELVVLTPEQNRAPWFPRSWTSVYPLALLQRTYTLLRRR
NGAPVQIPEDVQQLVDDVYDDDSLAEDLEADMERMGEELAQRGLARNAVI
PDPDDAEDNLNGLTEFATRFGAGSVRVLCYYVGNRWLDPECTVEFPEQGT
GREGRFTMADCRDLVARTIPVRMGPWASQLTEDNHPPEAWRESFYLRDLV
LIPQRVTDEGAVLPTETGGREWLLDPCKGLIF
Ligand information
Receptor-Ligand Complex Structure
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PDB6c66 Structure basis for RNA-guided DNA degradation by Cascade and Cas3.
Resolution3.66 Å
Binding residue
(original residue number in PDB)
D84 K87 H115 H150 D215 W216 R412
Binding residue
(residue number reindexed from 1)
D71 K74 H102 H137 D202 W203 R326
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0051607 defense response to virus
Cellular Component
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6c66, PDBe:6c66, PDBj:6c66
PDBsum6c66
PubMed29880725
UniProtQ47PJ0

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