Structure of PDB 5tvp Chain G Binding Site BS01

Receptor Information

>5tvp Chain G (length=249) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SSTISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAY
LKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLC
VNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFA
GDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAA
YKHRFDRIFFRAEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVV

Ligand information

>5tvp Chain P (length=9) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ccgaattcg

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5tvp ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Resolution	2.399 Å
Binding residue (original residue number in PDB)	I317 P318
Binding residue (residue number reindexed from 1)	I197 P198

Enzymatic activity

Enzyme Commision number

3.1.4.-

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity

View graph for
Molecular Function

External links

PDB	RCSB:5tvp, PDBe:5tvp, PDBj:5tvp
PDBsum	5tvp
PubMed	28912134
UniProt	Q9JJX7\|TYDP2_MOUSE Tyrosyl-DNA phosphodiesterase 2 (Gene Name=Tdp2)

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