Structure of PDB 5fvc Chain G Binding Site BS01

Receptor Information
>5fvc Chain G (length=368) Species: 162145 (human metapneumovirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEI
LYAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSQM
LDIHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPIILLC
VGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARSFYDL
FEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGV
IARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPKAGLL
SLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLKESNK
INFSSLGLTDEEKEAAEH
Ligand information
>5fvc Chain K (length=70) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccccccccccccccccccccccccccccccccccccccccccccccccc
cccccccccccccccccccc
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Receptor-Ligand Complex Structure
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PDB5fvc Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein.
Resolution4.17 Å
Binding residue
(original residue number in PDB)		K171 S174 R185 R186 R189 V190 L243 N246 Q250 G255 T257 W261 M337 Y338 R339 G340 R341
Binding residue
(residue number reindexed from 1)		K158 S161 R172 R173 R176 V177 L230 N233 Q237 G242 T244 W248 M324 Y325 R326 G327 R328
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5fvc, PDBe:5fvc, PDBj:5fvc
PDBsum5fvc
PubMed26880565
UniProtQ91F57

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