Structure of PDB 5ejk Chain G Binding Site BS01

Receptor Information

>5ejk Chain G (length=250) Species: 11888 (Rous sarcoma virus - Prague C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PLREAKDLHTALHIGPRALSKASNISMQQAREVVQTCPHCPRGLGPLQIW
QTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAVQHHWATAIAV
MGRPKAIKTDNGSCFTSKSTREWMARWGIAHTTGAMVERANRMMKDKIRV
LAEGDGFMKRIPTSKQGEMMAKAMYALNHFERGENTKTPIQKHWRPTVLT
EGPPVKIRIETGEWEKGWNVLVWGRGYAAVKNRDTDKVIWVPSRKVKPDI

Ligand information

>5ejk Chain M (length=18) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aatgttgtcttatgcaat

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	5ejk Crystal structure of the Rous sarcoma virus intasome.
Resolution	3.8 Å
Binding residue (original residue number in PDB)	R53 G245 Y246 W259 R263
Binding residue (residue number reindexed from 1)	R42 G226 Y227 W240 R244

Enzymatic activity

Enzyme Commision number

2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0008270	zinc ion binding

	Biological Process
GO:0015074	DNA integration

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:5ejk, PDBe:5ejk, PDBj:5ejk
PDBsum	5ejk
PubMed	26887497
UniProt	P03354\|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)

[Back to BioLiP]