Structure of PDB 5edn Chain G Binding Site BS01

Receptor Information
>5edn Chain G (length=60) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNR
RVKEKKVLAK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5edn Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K225 G226
Binding residue
(residue number reindexed from 1)		K8 G9
Binding affinityPDBbind-CN: Kd=46nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5edn, PDBe:5edn, PDBj:5edn
PDBsum5edn
PubMed29638214
UniProtQ92826|HXB13_HUMAN Homeobox protein Hox-B13 (Gene Name=HOXB13)

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