Structure of PDB 4x4p Chain G Binding Site BS01

Receptor Information
>4x4p Chain G (length=428) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARN
TWLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAEHPYVH
GVVKGVEVDVVPCYKSAVDRTPFHHKWLEGRIKGKENEVRLLKGFLKANG
IYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVIDVAKGEVR
KGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSLGFFKPKHP
LEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERASRKIFEFLE
RENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFEDERNVKKFL
SRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLGKNVGESIR
EYFEIISGEKLFKEPVTAELCEMMGVKD
Ligand information
>4x4p Chain H (length=28) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggccgcggcagguucgauccugccgcca
<<<...<<<<<<......>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB4x4p On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A95 A163 Y165 R224 A228 N229 D291 N292 P295 R344 P347 N354 K357 F358 H396 H398 T399 K402
Binding residue
(residue number reindexed from 1)		A94 A154 Y156 R215 A219 N220 D282 N283 P286 R335 P338 N345 K348 F349 H387 H389 T390 K393
Enzymatic activity
Enzyme Commision number 2.7.7.72: CCA tRNA nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0160016 CCACCA tRNA nucleotidyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0008033 tRNA processing
GO:0031123 RNA 3'-end processing
GO:0042245 RNA repair
GO:0106354 tRNA surveillance

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Molecular Function
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Biological Process
External links
PDB RCSB:4x4p, PDBe:4x4p, PDBj:4x4p
PDBsum4x4p
PubMed25640237
UniProtO28126|CCA_ARCFU CCA-adding enzyme (Gene Name=cca)

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