Structure of PDB 4wu8 Chain G Binding Site BS01

Receptor Information
>4wu8 Chain G (length=106) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEIL
ELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQS
VLLPKK
Ligand information
>4wu8 Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagatactaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctgaatcagctgaacatgccttttgatggagc
agtttccaaatacacttttggtagtatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB4wu8 Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Resolution2.45 Å
Binding residue
(original residue number in PDB)
R29 R35 R42 V43 G44 A45 K75 T76 R77
Binding residue
(residue number reindexed from 1)
R16 R22 R29 V30 G31 A32 K62 T63 R64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:4wu8, PDBe:4wu8, PDBj:4wu8
PDBsum4wu8
PubMed25916851
UniProtP06897|H2A1_XENLA Histone H2A type 1

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