Structure of PDB 4qqx Chain G Binding Site BS01

Receptor Information
>4qqx Chain G (length=887) Species: 269800 (Thermobifida fusca YX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYLSPGLRDTIAS
SMETDEEHAGHCIAFWAGLHDIGKLTREFQQQIAIDLSAYPGEELSGEQR
SHAAATGKWLPFALPSLGYPNGGLVTGLVAQMLGGHHGTFHPHPSFQSRN
PLAEFGFSSPHWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL
ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPSLLDAAGLRPI
TVPPATFTESFPHLSKPNGLQASLAKHLPCLCTGPGLVLITAPMGEGKTE
AAYHVADLLGKATGRPGRFLALPTMATADQMHTRLKEYARYRVESSTLAL
LHSMAWLNPDYAPADPFAATDWLMGRKRGLLAPWAVGTIDQALMAVLRAK
HNALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGTLDVPVVLLSAT
LHHSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDARIGKVTR
SSDVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLAKELTPLVKQAAI
ICTTVAEAQGVYDLLSQWFATLPDLYLLHSRFPNRQRTEITATIVDLFGK
EGAQSGRRPTVLVATQVVEQSLDLDVDLMISDLAPVSLLLQRAGRCWRHE
HLGIINRPQWAKQPELVVLTPEQNRAPWFPRSWTSVYPLALLQRTYTLLR
RRNGAPVQIPEDVQQLVDDVYDDDSLAEDLEADMERMGEELAQRGLARNA
VIPDPDDAEDNLNGLTEFSVLATRFGAGSVRVLCYYVGNRWLDPECTVEF
PEQGTGREGRFTMADCRDLVARTIPVRMGPWASQLTEDNHPPEAWRESFY
LRDLVLIPQRVTDEGAVLPTETGGREWLLDPCKGLIF
Ligand information
Receptor-Ligand Complex Structure
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PDB4qqx Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Resolution3.34 Å
Binding residue
(original residue number in PDB)
K23 D84 K87 H150 D215 W216 S219 E221 T337 M338 H371 S372 R410 K411 R412 T422 D424 T590 T591 V592 S621 T659 Q660 Q664 R729 S730 S733 V734 R828 G832 S833 R884
Binding residue
(residue number reindexed from 1)
K10 D71 K74 H137 D202 W203 S206 E208 T324 M325 H352 S353 R376 K377 R378 T388 D390 T553 T554 V555 S580 T615 Q616 Q620 R681 S682 S685 V686 R774 G778 S779 R827
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0051607 defense response to virus
Cellular Component
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4qqx, PDBe:4qqx, PDBj:4qqx
PDBsum4qqx
PubMed25132177
UniProtQ47PJ0

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