Structure of PDB 4gwq Chain G Binding Site BS01

Receptor Information
>4gwq Chain G (length=170) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNVTPLDELQWKSPEWIQVFGLRTENVLDYFAESPFFDKTSNNQVIKMQR
QFSQLNDPNAFAYVDPARRQILFKYPMYMQLEEELMKLDGTEYVLSSVRE
PDFWVIRKQRRTNNSGVGSAKGPEIIPLQDYYIIGANIYQSPTIFKIVQS
RLMSTSYHLNSTLESLYDLI
Ligand information
>4gwq Chain H (length=25) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PSYSPTSPSYSPTSPSYSPTSPSYS
Receptor-Ligand Complex Structure
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PDB4gwq Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		L9 Q10
Binding residue
(residue number reindexed from 1)		L9 Q10
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
GO:0060261 positive regulation of transcription initiation by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
GO:0070847 core mediator complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gwq, PDBe:4gwq, PDBj:4gwq
PDBsum4gwq
PubMed23071300
UniProtP38782|MED6_YEAST Mediator of RNA polymerase II transcription subunit 6 (Gene Name=MED6)

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