Structure of PDB 3u9m Chain G Binding Site BS01

Receptor Information
>3u9m Chain G (length=157) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKE
FKMHEQIENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEY
EQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKK
VIAQHCS
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain3u9m Chain G Residue 207 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3u9m The Structural Basis of Iron Sensing by the Human F-box Protein FBXL5.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		E58 E61 H80 H126 E130
Binding residue
(residue number reindexed from 1)		E55 E58 H77 H123 E127
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006879 intracellular iron ion homeostasis

View graph for
Biological Process
External links
PDB RCSB:3u9m, PDBe:3u9m, PDBj:3u9m
PDBsum3u9m
PubMed22492618
UniProtQ9UKA1|FBXL5_HUMAN F-box/LRR-repeat protein 5 (Gene Name=FBXL5)

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