Structure of PDB 3lnz Chain G Binding Site BS01

Receptor Information
>3lnz Chain G (length=84) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIV
YCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVV
Ligand information
Receptor-Ligand Complex Structure
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PDB3lnz Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		F55 Y56 Q59
Binding residue
(residue number reindexed from 1)		F30 Y31 Q34
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3lnz, PDBe:3lnz, PDBj:3lnz
PDBsum3lnz
PubMed20226197
UniProtQ00987|MDM2_HUMAN E3 ubiquitin-protein ligase Mdm2 (Gene Name=MDM2)

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